Question:

What is the significance of the addition of the phrase ‘when performed’ in the revised descriptors for CPT® codes 93571 and 93572?

Answer:

Historically, the definitions for 93571 and 93572 explicitly required a pharmacologic agent. As a result, iFR and DFR—both non-hyperemic methods—were handled inconsistently between professional and facility coding. The AMA directed physicians to use 93571 or 93572 with modifier 52 when hyperemia was not induced. In contrast, the AHA instructed hospitals to avoid 93571/93572 altogether and instead use 93799 for non-hyperemic assessment. The 2026 revision finally resolves this discrepancy. By adding the phrase “when performed,” the descriptor now formally recognizes that intravascular flow reserve may be performed with or without pharmacologic stress. This allows accurate reporting without relying on modifiers or unlisted codes. This alignment will significantly simplify both workflow and audit processes moving forward.

This question was answered in our annual Cardiology Reimbursement & Compliance Update webcast. For more hot topics relating to cardiology services, please visit our store or call us at 1.800.252.1578, ext. 2.

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