Laboratory Question for the Week of January 5, 2026
Under what circumstances can code 80051 be reported multiple times?
Mounting complexity, confusing new rules, new technologies, and diminishing reimbursements could place laboratory coding and compliance into peril, with lost revenue on the table and potential risk for audits. If you’re involved with coding and billing for molecular pathology, molecular biology, cytogenics or drug-of-abuse testing, you know exactly what we’re talking about! How can you possibly keep up with the continual advances?
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Under what circumstances can code 80051 be reported multiple times?
Can we append modifier 91 for the billing of multiple units of the organ and disease panel codes 80047 and 80048?
What compliance and billing challenges can arise when multiple hospital departments perform laboratory testing, particularly with point-of-care testing (POCT)? In this regard, do you have any insight into billing modifier 91?
When is modifier 91 applicable for testing?

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