Microbiologist Sees Hope in COVID-19 Genomic Sequence

EDITOR’S NOTE: Julia Brodt is the wife of John K. Hall, MD, a member of the RACmonitor Editorial Board and guest panelist on Monitor Mondays.

I am a scientist, teacher, wife, daughter, mother, friend, and an American. I was born in Cincinnati, Ohio – home to Cincinnati Reds baseball, large companies like Procter & Gamble (dubbed Procter and God by the natives), the Kroger Co., delicious Skyline Chili, and Albert Sabin. Dr. Sabin and his team developed an oral vaccine for polio at the Cincinnati Children’s Hospital in 1960. Polio was a terrifying disease in its day, thought to be transmitted in pool water to unsuspecting victims, potentially causing paralysis or death – much like our morbid death watch for COVID-19.

You see, I know about disease. It thrills and fascinates me to study all aspects of the unknown. I have spent years tucked away in windowless, friendless laboratories, doing research that produced expected results less than 10 percent of the time. Sometimes, it required revision of one’s hypothesis, because data does not lie. When an experiment works, it provides a “high” like no other. On a regular basis, I passed the display about Dr. Sabin and felt admiration for his tenacity in difficult times. I, and countless others, have benefitted from his contribution to the polio vaccine.

I have used my knowledge to teach students about the human body and infectious disease. We proclaimed victory with the discovery of penicillin and the advent of other antibiotics, but microbes continue to mutate and outsmart us. In teaching epidemiology, I explained how flu viruses cross-infect species and change, mainly in China, where animals live in close proximity with people. As we can quickly travel great distances, those microbes may be carried in people, or on manufactured products and foods. We have evaded the Ebola virus in great part because it can rapidly kill its host. COVID-19 is more insidious in action.

My anxious curiosity was somewhat satisfied with publication of COVID-19’s genomic sequence, which helped answer in part questions like “How dissimilar is it to other coronaviruses? What makes this bug so infectious?” Clues lie in COVID-19’s genetic code. My questions continued, thusly addressed in online conversations with members of a scientific honor society and colleagues. The computer has become my classroom as I teach online from home, with no face-to-face contact with college students for the foreseeable future.

Our lives have changed. We quarantine at home. My daughter finished her school year by teaching elementary students online. My other daughter, an ICU nurse, was exposed to COVID-19 early in the pandemic, then fought to get tested (which thankfully turned out negative), and my son finished his college degree with no graduation ceremony; rather, a family Zoom session sufficed.

During this outbreak, my husband has worked on the front lines within a hospital system. He goes to his job, then returns home to change clothes and wash up for dinner. In all our medical advancements, hand-washing with soap and water still provides our best defense against infectious disease. He buys produce during “senior hours,” I cook at home, and we purchase other goods through Amazon, which safely delivers to our door. I wash our clothes, sheets, and towels more often, and the five-second rule for foods dropped on the floor no longer applies. My husband hands me vitamin B and D pills to take daily. I swim in our backyard pool with chlorinated water that should quickly counteract a virus. I no longer sing in choir; members visit by computer during our practice time, and we catch up virtually. Our community band concert was canceled in March, and we cannot practice as a group. No emails have been sent with plans because we practice inside a school, in a room where we must sit shoulder to shoulder.

At the onset of the epidemic, I found Internet directions for making masks, and shipped them out to the family, as they can decrease the spread of droplets that carry virus particles. I later ordered masks for my parents, when it became apparent we were in this for the long haul. People of all varieties have been affected, but some groups are at greater risk for infection: those deemed immunocompromised, for example, such as the elderly or folks with underlying health conditions. I believe that “no virus is a good virus,” unless you count the ones that have been attenuated for use in vaccines or successfully used as vectors for transfer of genetic information in labs.

I hesitate to use the word, “unprecedented” for our COVID-19 situation, because humanity has previously traveled this road many times. People have perished and survived waves of the plague, smallpox, the Influenza Epidemic of 1918, polio, AIDS, and more recently, SARS and MERS. What is new to our generational experience is that we do not have the magic medicine to make it all end right now. We want what we want when we want it! I understand that we do not wish to see our family members, or any living person, suffer and die. I wish China had given the world a heads-up that this virus was coming. But be patient, remain diligent with hand-washing, stay socially distanced, wear a mask, eat nutritious food, get necessary hours of sleep, exercise, meditate, and be kind to one another.

Today we have far greater knowledge than the days when Dr. Sabin conducted his testing. I have no doubt that scientific minds will prevail this time around, and hopefully the next….                                                     

Facebook
Twitter
LinkedIn

Related Stories

Leave a Reply

Please log in to your account to comment on this article.

Featured Webcasts

Trending News

Featured Webcasts

Ask Dr. Hirsch: Clarifying Medicare’s Most Misunderstood Rules – Part 2

Medicare regulations are complex and even seasoned professionals struggle to apply them consistently. Due to overwhelming demand, Dr. Hirsch returns for Part 2 of Ask Dr. Hirsch: Clarifying Medicare’s Most Misunderstood Rules to answer even more of Medicare’s most misunderstood questions, covering inpatient status, observation, SNF access, Medicare Advantage denials, and more. Join Dr. Hirsch as he provides clear, referenced answers to real-world questions submitted by your peers, helping you navigate Medicare compliance with confidence and clarity.

June 18, 2026

Reengineering Utilization Management: Building an Adaptive Model for the New Payer Era

Traditional utilization management models can no longer keep pace with regulatory shifts, payer scrutiny, and operational pressures. In this webcast, Tiffany Ferguson, LMSW, CMAC, ACM, ACPA-C, introduces an Adaptive Model strategy that modernizes UM through role specialization, technology-driven workflows, and proactive, team-based processes. Attendees will learn how to restructure programs to improve efficiency, strengthen clinical collaboration, and enhance financial performance in a rapidly changing healthcare environment.

May 20, 2026

Compliance for the Inpatient Psychiatric Facility (IPF-PPS): Minimizing Federal Audit Findings by Strengthening Best Practices

Federal auditors are intensifying their focus on inpatient psychiatric facilities, using advanced data analytics to spotlight outliers and pursue high‑dollar repayments. In this high‑impact webcast, Michael Calahan, PA, MBA, Compliance Officer and V.P., Hospital & Physician Compliance, breaks down what regulators are really targeting in IPF-PPS admissions, documentation, treatment and discharge planning. Attendees will learn practical steps to tighten processes, avoid common audit triggers and protect reimbursement and reduce the risk of multimillion-dollar repayment demands.

April 9, 2026

Mastering MDM for Accurate Professional Fee Coding

In this timely session, Stacey Shillito, CDIP, CPMA, CCS, CCS-P, CPEDC, COPC, breaks down the complexities of Medical Decision Making (MDM) documentation so providers can confidently capture the true complexity of their care. Attendees will learn practical, efficient strategies to ensure documentation aligns with current E/M guidelines, supports accurate coding, and reduces audit risk, all without adding to charting time.

March 31, 2026

Trending News

Celebrate Lab Week with MedLearn! Sign up to win one year of our Laboratory All Access Pass! Click here to learn more →

Have a Medicare regulation question you’d love Dr. Hirsch to answer? Now is your chance! CLICK HERE to learn more→

Happy National Doctor’s Day! Learn how to get a complimentary webcast on ‘Decoding Social Admissions’ as a token of our heartfelt appreciation! Click here to learn more →

This Memorial Day, we honor those who gave all for our freedom. Take 20% off sitewide through May 29 with code MEMORIAL26 at checkout

CYBER WEEK IS HERE! Don’t miss your chance to get 20% off now until Dec. 1 with code CYBER25

CYBER WEEK IS HERE! Don’t miss your chance to get 20% off now until Dec. 2 with code CYBER24